Sugarland will perform with Melissa Etheridge during the finale of Friday's 'Stand Up to Cancer' television broadcast. The star-studded special will air live on ABC, CBS and NBC at 8 PM ET. Other performers include LeAnn Rimes, Carrie Underwood, Miley Cyrus and Sheryl Crow. Star athletes and stars from the big and small screens will serve as announcers in the hour-long, commercial-free show.

Money raised from the broadcast will benefit Stand Up to Cancer, an organization that funds ground-breaking cancer research. To find out how you can help, visit the SU2C website.