The video for Lady Antebellum's single, 'American Honey,' world premiered exclusively on Oprah.com on Friday morning. The clip is the first music video the talk show host has ever debuted, and its premiere coincides with the trio's first appearance on Oprah's television show, on which they performed a medley of their No. 1 hits 'Need You Now' and 'Run to You.'

"We knew we had to have it when we heard it," Lady A's Dave Haywood tells The Boot. "It's one that features Hillary on lead. And I think it's a message that we want to have out there that as crazy as the times get for our job and anybody's job, you have to remember when life was a little simpler and a little sweeter." 'American Honey' is the second single from their 'Need You Now' album; the first single and title track held court at the top of the country charts for five weeks.

Lady Antebellum is currently out with Tim McGraw on his Southern Voice tour, and they hit Roanoke, Va. on Friday and Huntington, W.V. on Saturday.

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