The ACM Awards are known as much for their jaw-dropping performances as the trophies they hand out, and this year promises to be no exception.

Blake Shelton will take the stage during the live televised show to perform with his fellow judge on 'The Voice,' Shakira. The two will perform their duet, 'Medicine,' which appears on her new, self-titled album.

“I kind of directed him,” the songstress says of the collaboration. “I wrote the song with some people from Nashville and I sent it to him and I was super-nervous. I was like, ‘Oh my god. What’s he going to think?’ And he loved it. He said, ‘Wow! This is exactly what you were talking about. I love this song.’”

Shakira won't be the only non-country artist who will sing during the ceremony. Stevie Nicks will also perform, alongside Lady Antebellum. Other confirmed artists include Eric Church, Toby Keith, Keith Urban, Jason Aldean, Miranda Lambert, George Strait, the Band Perry and Hunter Hayes. See a complete list of performers here.

The 49th annual ACM Awards, hosted by Shelton and Luke Bryan, will air live from Las Vegas on Sunday, April 6 at 8PM ET on CBS. See a complete list of nominees here.